ingredient
The main component of this product is chloramphenicol.
Traits
This product is a pale yellow or yellow ophthalmic ointment.
Indication
This product is used to treat conjunctivitis, keratitis, orbital blepharitis, trachoma caused by Escherichia coli, Haemophilus influenzae, Klebsiella, Staphylococcus aureus, hemolytic streptococcus and other sensitive bacteria.
Pharmacological action
1. This product is a chloramphenicol antibiotic. It has a broad-spectrum antimicrobial effect in vitro, including aerobic Gram-negative bacteria and Gram-positive bacteria, anaerobic bacteria, Rickettsia, spirochetes and Chlamydia.
2. Sterilization of the following bacteria: Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis.
3. It has only bacteriostatic effects on the following bacteria: Staphylococcus aureus, Streptococcus pyogenes, Streptococcus viridans, Group B hemolytic streptococcus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Anaerobic bacteria such as Salmonella paratyphimurium, Shigella, and Bacteroides fragilis.
4. The following bacteria are usually resistant to chloramphenicol: Pseudomonas aeruginosa, Acinetobacter, Enterobacter, Serratia marcescens, Proteus-positive Proteus, Methicillin-resistant Staphylococcus and Enterococcus Genus. This product is a bacteriostatic agent. Chloramphenicol is fat-soluble, diffuses into bacterial cells, and reversibly binds to the 50S subunit of bacterial ribosomes, hindering the growth of peptide chains (possibly due to inhibition of transpeptidase), thus inhibiting peptide chains Formation, thereby preventing protein synthesis.
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