Sodium Lactated Ringer's Injection, Western medicine name. For body fluids, electrolytes, acid-base balance regulators. For metabolic acidosis or dehydration cases with metabolic acidosis.
Element
This product is a compound preparation, its components are sodium lactate, sodium chloride, potassium chloride, calcium chloride.
traits
This product is a colorless clear liquid.
Indications
This product is used for metabolic acidosis or dehydration cases with metabolic acidosis.
Specification
(1) 500ml: sodium lactate 1.55g, sodium chloride 3.0g, potassium chloride 0.15g, calcium chloride 0.10g; (2) 1000ml: sodium lactate 3.10g, sodium chloride 6.00g, potassium chloride 0.30g, chloride Calcium 0.20g.
Dosage
Intravenous drip. Adults take 500ml-1000ml at a time, which can be appropriately increased or decreased according to age, weight and symptoms. Dosing rate: 300-500ml per hour for adults.
Adverse reactions
1. People with hypocalcemia (such as uremia) are prone to symptoms such as numbness in the hands and feet, pain, twitching, and difficulty breathing after correcting acidosis, which is often caused by a decrease in blood hydrogen calcium ion concentration.
2. Accelerated heart rate, chest tightness, shortness of breath and other manifestations of pulmonary edema and heart failure.
3. Increased blood pressure.
4, weight gain, edema.
5. Alkalosis occurs when overdose.
6. Decreased serum potassium concentration and sometimes hypokalemia.
taboo
1. Contraindicated in patients with heart failure and acute pulmonary edema.
2. Patients with cerebral edema are disabled.
3. It is disabled when lactic acidosis is significant.
4. Patients with severe hepatic insufficiency are disabled.
5. Patients with severe renal failure with oliguria or anuria are prohibited.
Precautions
1. It should be used with caution in the following situations:
(1) Diabetic patients taking biguanide drugs (especially Jiangtangling) hinder the utilization of lactic acid by the liver and easily cause lactic acidosis.
(2) When edema patients are accompanied by sodium retention tendency.
(3) Hypertensive patients can increase blood pressure.
(4) Heart insufficiency.
(5) The degradation rate of lactic acid is slowed down in the case of liver insufficiency, so as to delay the correction rate of acidosis.
(6) Hypoxia and shock, insufficient blood supply to tissues and hypoxia, the oxidation of lactic acid into procupric acid into the tricarboxylic acid cycle slows down the metabolism, so as to delay the correction of acidosis.
(7) Lactic acidosis tends to occur in alcoholism, salicylic acidosis, and type I glycogen deposition disease, and sodium lactate should not be used to correct the acid-base balance.
(8) Acetoacetic acid, β-hydroxybutyric acid and lactic acid are all elevated in diabetic copper acidosis, and are often accompanied by poor circulation or insufficient blood supply to organs, and the degradation rate of lactic acid is slowed down.
(9) Renal insufficiency, prone to water and sodium retention, and increased cardiovascular load.
2. The following conditions should be disabled:
(1) Heart failure and acute pulmonary edema.
(3) Cerebral edema.
(3) When lactic acidosis has become obvious.
(4) Severe hepatic insufficiency.
(5) Severe renal failure with oliguria or anuria.
3. The following inspections and observations should be made when taking medication:
(1) Blood pH and/or carbon dioxide binding capacity.
(2) Determination of blood sodium, potassium, calcium and chloride concentrations.
(3) Determination of renal function, including blood muscle liver, blood urea nitrogen, etc.
(4) Blood pressure.
(5) Cardiopulmonary function status, such as edema, shortness of breath, cyanosis, pulmonary rales, jugular vein filling, liver-jugular venous reflux, etc., venous pressure or central venous pressure should be measured as needed.
(6) Liver insufficiency manifests as jaundice, mental changes, ascites, etc., and should be observed at any time before and during the application of sodium lactate.
medicine interactions
1. When used in combination with other drugs, pay attention to the incompatibility of drugs (such as macrolide antibiotics, alkaloids, sulfonamides) due to changes in pH and ionic strength.
2. Since this product contains calcium ions, it will cause precipitation when mixed with blood containing sodium citrate.
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