Lincomycin hydrochloride capsules, western medicine name. For antibacterial drugs. It is used for respiratory infections, skin and soft tissue infections, female reproductive tract infections, pelvic infections and abdominal infections caused by sensitive Staphylococcus, Streptococcus, Streptococcus pneumoniae and anaerobic bacteria. In addition, patients with penicillin indications, such as patients who are allergic to penicillin or who are not suitable for penicillin, this product can be used as an alternative medicine.
Element
The main ingredient of this product is lincomycin hydrochloride.
Traits
The content of this product is white crystalline powder.
Indications
This product is suitable for respiratory infections, skin and soft tissue infections, female reproductive tract infections, pelvic infections and abdominal infections caused by sensitive Staphylococcus, Streptococcus, Streptococcus pneumoniae and anaerobic bacteria. In addition, patients with penicillin indications, such as patients who are allergic to penicillin or who are not suitable for penicillin, this product can be used as an alternative medicine.
Specification
Calculated according to C18H14N2O6S: 0.25g.
Dosage
1. This product should be taken on an empty stomach, 1.5-2g a day for adults, 3-4 times orally.
2. Children take 30-60mg/kg daily, 3-4 times orally; infants younger than 4 weeks should not take it.
Adverse reactions
1. Gastrointestinal reactions: common nausea, vomiting, abdominal pain, diarrhea, etc.; severe cases include abdominal cramps, abdominal tenderness, severe diarrhea (watery or pus-blood samples), accompanied by fever, abnormal thirst and fatigue (pseudomembranous enteritis) ); Diarrhea, enteritis and pseudomembranous enteritis can occur in the initial stage of medication, and can also occur several weeks after stopping the medication.
2. Blood system: Leukopenia, neutropenia, eosinophilia and thrombocytopenia may occasionally occur. Rare aplastic anemia.
3. Allergic reactions: skin rash, itching, etc., occasionally urticaria, angioedema and serum sickness reactions. Exfoliative dermatitis, bullous dermatitis, erythema multiforme and Stevens-Johnson syndrome are rare.
4. Abnormal liver and kidney function, such as elevated serum aminotransferase, jaundice, etc.
5. Others: tinnitus, dizziness, candida infection, etc.
Taboo
Patients who have a history of allergies to this product and clindamycin are contraindicated.
Precautions
1. The following patients should be used with caution:
(1) Patients with gastrointestinal diseases or past history. Especially such as ulcerative colitis, localized enteritis or antibiotic-related enteritis (this product can cause pseudomembranous enteritis).
(2) Patients with reduced liver function.
(3) Patients with severely decreased renal function.
(4) Those with a history of asthma or other allergies.
2. When you are allergic to this product, you may also be allergic to other lincomycins.
3. Elderly patients who need to undergo regular testing of liver and kidney functions and blood routines.
4. This product cannot penetrate the blood-cerebrospinal fluid barrier, so it cannot be used for meningitis.
5. In order to prevent the occurrence of acute rheumatic fever, when using this product to treat hemolytic streptococcus infection, the course of treatment should be at least 10 days.
6. Interference with laboratory test indicators: Serum alanine aminotransferase and aspartate aminotransferase may increase after taking the drug.
7. During medication, you should pay close attention to the frequency of bowel movements. If the frequency of bowel movements increases, you should pay attention to the possibility of pseudomembranous enteritis. The medication should be stopped in time and appropriate treatment should be performed. Mild patients may recover after stopping the drug; moderate to severe patients need to supplement water, electrolytes and protein. If the above treatment is ineffective, 250-500mg of metronidazole should be taken orally 3 times a day. In case of recurrence, metronidazole can be taken orally again, or vancomycin (or norvancomycin) can be used if it is still ineffective, 125-500 mg once, once every 6 hours, and the course of treatment is 5-10 days.
8. This product will occasionally lead to the over-proliferation of insensitive microorganisms or cause double infection. Once double infection occurs, corresponding measures must be taken.
9. For patients with severe renal dysfunction and/or severe liver dysfunction, accompanied by severe metabolic abnormalities, blood drug concentration monitoring is required when using high doses.
10. The susceptibility of different bacteria to this product may be quite different, so the drug susceptibility test is of great significance.
11. Medication for pregnant women and lactating women: This product can be concentrated in the liver of the fetus after passing through the placenta. The pros and cons of pregnant women need to be fully weighed. This product can be secreted into breast milk, and breastfeeding women should also use it with caution. If it must be used, breastfeeding should be suspended.
12. Children's medication: infants younger than 1 month should not be used.
13. Elderly medication: Elderly people with serious underlying diseases are prone to adverse reactions such as diarrhea or pseudomembranous enteritis, and they need to be closely observed during medication.
14. Drug overdose: Symptomatic therapy and supportive therapy are mainly used for drug overdose, such as gastric lavage, emetics and fluid supplements.
storage
Keep sealed.
Valid period
24 months
Executive standard
Audited Supplier 
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