Element
The main ingredient of this product is albendazole.
Traits
This product is white-like tablets, sugar-coated tablets or film-coated tablets, which will appear white or almost white after removing the coating.
Indications
This product is a broad-spectrum anthelmintic. In addition to the treatment of hookworm, roundworm, whipworm, pinworm, trichinella and other nematode diseases, it can also be used for the treatment of cysticercosis and echinococcosis.
Specification
(1) 0.1g; (2) 0.2g; (3) 0.4g.
Dosage
oral.
1. Common dosage for adults:
(1) Ascaris and pinworm disease, 0.4g per time, take a meal.
(2) Hookworm disease, whipworm disease, 0.4g once, twice a day, for 3 days.
(3) Trichinosis, 0.4g once, twice a day, for 7 days.
(4) Cysticercosis, take 20mg/kg daily according to body weight, orally in 3 doses, 10 days is a course of treatment, generally 1-3 courses are required. The interval between treatments depends on the condition, usually 3 months.
(5) Hydatid disease, take 20mg/kg daily according to body weight, orally in 2 doses. The course of treatment is 1 month. Generally, it takes more than 5 courses and the interval between treatments is 7-10 days.
2. Pediatric dosage: the dosage for children under 12 years old is halved.
Clinical application and guidelines
Wei Xiaolong and Tan Ruibin analyzed the clinical efficacy and side effects of albendazole tablets and praziquantel tablets in the treatment of liver flukes, and concluded that the clinical efficacy of albendazole tablets and praziquantel tablets in the treatment of liver flukes is equivalent, but albendazole Tablets have fewer adverse effects in treatment and higher safety. Clinically, they can be selected reasonably according to actual conditions. (Electronic Journal of Modern Medicine and Health Research, 2018, 2(13):73-74.)
Adverse reactions
1. A few cases have gastrointestinal symptoms such as dry mouth, fatigue, sleepiness, dizziness, headache, nausea, and upper abdominal discomfort. However, they are relatively mild and can relieve themselves without treatment.
2. In the treatment of cysticercosis, especially cerebral cysticercosis, it is mainly related to the death of cysticercosis and the release of heterosexual protein, which occurs more than 2-7 days after taking the medicine, such as headache, fever, rash, muscle aches, visual impairment, seizures, etc. Corresponding measures must be taken (application of adrenal cortex hormones, lowering intracranial pressure, anti-epileptic treatment, etc.).
3. For the treatment of cysticercosis and echinococcosis, due to the larger dosage and longer course of treatment, alanine aminotransferase may increase, which will gradually return to normal after stopping the drug.
Taboo
1. Patients with proteinuria, purulent dermatitis and various acute diseases.
2. Patients with severe liver, kidney, heart insufficiency and active ulcer disease.
3. Before surgical removal of cysticercosis.
Precautions
1. Enterobiasis is easy to reinfect itself, so the treatment should be repeated once after 2 weeks of treatment.
2. Patients with cerebral cysticercosis must be hospitalized to avoid accidents.
3. When combined with ocular cysticercosis, surgical removal of the parasites must be performed first, followed by drug treatment.
storage
Keep sealed.
Valid period
30 months
Executive standard
Chinese Pharmacopoeia 2015 edition two.
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